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In order to find out whether ceftriaxone, a third generation cephalosporin antibiotics, is used appropriately, safely and effectively, DUE study was conducted by reviewing 70 charts of patients who were treated at Kangnam St. Mary´s hospital from Oct. 1997 to Nov. 1997. The DUE criteria was modified from the criteria on ceftriaxone use established by American Society of Health-System Pharmacists. As a result, 33 cases (47.2%) were met with criteria for the justification of use. The analysing process indicators including CBC, SCr were taken before the initial dose and the vital sign monitoring were relatively well documented showing the accepted levels of above 80%. On the other hand, blood sampling for the culture and sensitivity test before the initial antibiotic dose WBC Count, SCr, LFT during the therapy were in low accepted levels. As an outcome analysis, the result of blood culture after discontinuing drug were documented with accepted level of 24.3%. As a conclusion, it is suggested that above finding should be communicated to the medical staff, and an active intervention, such as feedback control system by pharmacist, also be necessary for the rational medication use.
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